Bubbling up on more than 100 islands in a lagoon off the Adriatic, Venice is an absolutely unique and unquestionably beautiful city. The weight of its opulent architecture – bulbous domes, gothic spires, and lacy marble – may be sinking the city by 10 inches a century, but your local guide will make sure you don’t sink out of sight as you tour the intricate labyrinth of streets and bridges. Step into Piazza San Marco, an airy expanse of arches, sunlight, and pigeons. The multi-domed Basilica on one end, completed in 1094 but decorated for centuries afterward, is the final resting place of the apostle St. Mark, Venice’s patron saint. The mosaics beneath the basilica’s outside arches depict the arrival of St. Mark’s body, stolen from Egypt in 828 by Venetian traders. The frothy Venetian Gothic Doge’s Palace stands next door. Continue on to a glass-blowing demonstration. Venetian glass has long been considered the best in the world, and its production was such a state secret that during the Middle Ages, any Venetian glassblower who attempted to ply his trade outside the city was immediately arrested.

Brush up on your Shakespeare before heading to Casa de Giuletta to gaze up (or down from, for a few euros more) the famed balcony that set the stage for star-crossed lovers Romeo and Juliet. Hear about the many versions of this tragic story that existed long before Shakespeare put his pen to it. Go from this battleground of love to a real gladiator’s Roman Arena. Theatre performances still take place in this third largest amphitheater in all of Italy, built in the 1st century B.C.

Immerse yourself in the charms of old-world Firenze, a red-brick splendor set in the rolling green hills of Tuscany. The birthplace and focal point of the Italian Renaissance, Florence still has the masterpieces to prove it. Brunelleschi’s elegant Duomo (dome) dominates the skyline, and around every corner is an architectural triumph filled with wall after wall of incomparable art. Your local licensed guide will take you to Giotto's Bell Tower and the aptly named Gates of Paradise, the bronze east doors of the Baptistery that spurred the burgeoning Renaissance. The boy guarding the Palazzo Vecchio with his slingshot is just a copy of Michelangelo’s David; the real statue is over at the Accademia. Don’t overlook the tombs of Michelangelo, Galileo, and Machiavelli at the Chiesa di Santa Croce, and definitely don’t overlook Florence’s amazing leather goods. Check them out when you visit one of the area’s famed workshops.

Stop in Pisa to see the famous leaning bell tower. It was already partly finished when builders realized that -- surprise! -- the ground beneath was too soft to support it. They tried to correct the tilt by putting a slight bend in the structure, but the extra weight just made it tilt more. Famous as it is, the leaning tower is just one component of Pisa’s Campo dei Miracoli (Field of Miracles). Rising from an immaculate green lawn, the baptistery, duomo, and tower are fine examples of Pisan Romanesque architecture. All three are clad in intricately carved black and white marble, and on bright summer days their brilliance can be blinding.

On the Mediterranean coast, five miles from the Italian border, lies the tiny, glittering independent state of Monaco. Ruled by the Grimaldi family since the 13th century, Monaco is the epitome of French Riviera glamour. Your Tour Director will lead you on this brief adventure. Charles III opened a casino in the 1850’s to avert financial straits; needless to say, his plan worked--so well, in fact, that Monaco is a nearly tax-free state. Drop in on Prince Rainier (OK, see his house, the Palais du Prince), and visit a parfumerie in nearby Èze, where rich scents are made from local flowers such as jasmine, rose, and lavender.

The Côte d'Azur's largest city spills down the hillsides to pebble beaches that line the shore. Your Tour Director will show you around the narrow pedestrian streets and tiny squares of "Le Vieux Nice" (Old Town), which is sprinkled with old palaces and mansions. Stroll down the Promenade des Anglais, which runs parallel to the water. Backed by Nice's grand hotels, the Promenade was built in the 19th century for the British who flocked here en masse.

The world's largest art museum, the Louvre is housed in a Medieval fortress-turned-castle so grand it's worth a tour itself. You walk through the 71-foot glass pyramid designed by I.M. Pei and added in 1989, and step into another world--one with carved ceilings, deep-set windows, and so many architectural details you could spend a week just admiring the rooms. The Mona Lisa is here, as well as the Venus de Milo and Winged Victory (the headless statue, circa 200 BC, discovered at Samothrace). The Louvre has seven different departments of paintings, prints, drawings, sculptures and antiquities. Don't miss the Egyptian collection, complete with creepy sarcophagi, or the collection of Greek ceramics, one of the largest in the world. (Please note the Louvre is closed on Tuesdays.)

What's that huge white arch at the end of the Champs-Élysées? The Arc de Triomphe, commissioned by Napoleon in 1806 after his victory at Austerlitz. Your licensed local guide will elaborate on this, and other Parisian landmarks. See some of the most famous sites, including the ornate, 19th-century Opera, the Presidential residence, the ultra-chic shops of the Rue du Faubourg St-Honoré, and the gardens of the Tuileries. You'll pass the Place de la Concorde, where in the center you’ll find the Obelisk of Luxor, a gift from Egypt in 1836, and the Place Vendôme, a huge square surrounded by 17th-century buildings. Spot chic locals (and tons of tourists) strolling the Champs-Élysées. Look up at the iron girders of the Eiffel Tower, built for the 1889 World's Fair to commemorate the centenary of the French Revolution. See Les Invalides (a refuge for war wounded), the École Militaire (Napoleon's alma mater), and the Conciergerie (the prison where Marie Antoinette was kept during the French Revolution).

See the city from the water on an hour-long cruise along the River Seine. The Seine cuts right through Paris, dividing the city in half. See the Eiffel tower rising up on the Left Bank, the walls of the Louvre on the Right Bank. A guide will point out other monuments and architectural marvels as you pass, many of which are illuminated by clear white light at night.